FDmiX Curiosity Multi-use. Easy and Sustainable Formulation Devleopment.

Like the Curiosity System, the Curiosity Multi-use System was specially developed for the rapid formulation development of LNP or polynanoparticles. The difference lies in the use of a reusable stainless steel mixer and an integrated fully automatic cleaning unit. The cleaning unit can be loaded with up to four cleaning liquids/rinsing solutions and an individual cleaning cycle can be set. This allows different active ingredients to be tested with one formulation.

The system will be available from Q4 2024. If you would like to test the system in advance or have any questions, please do not hesitate to contact us.

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At a glance. Product specifications.

The Curiosity multi-use system has two syringe pumps that can be operated with commercially available disposable syringes. An FDmiX mixer (XS) is connected to these and the piping is optimized to minimize dead volumes. The system also has an integrated, fully automatic cleaning unit. All materials used are approved for LNP encapsulation and we naturally also supply the corresponding material certificates. The following tables summarize the technical details once again. Please note that the flow rate and flow rates depend on the mixing ratio. Please contact us if you would like to test the system or have any questions.

Basic system
  • Fields of application: Formulation development LNP/polymer nanoparticles
  • Syringes (single-use)
  • Stainless steel mixer (multi-use)
  • Process volume: 2 – 7 ml @ (3:1 ratio)
  • Flow rate: 10 ml/min @ (3:1 ratio)
  • Integrated cleaning unit with up to 4 cleaning/rinsing solutions and programmable cleaning cycle
  • incl. control software
Accessories
  • Autosampler

(Screenshot of pump control software)

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FDmiX. From Lab to Fab.

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Customers. References.

In pilot tests conducted by the nanomanufacturing research group at the RCPE, the FDmiX technology platform delivered promising results for the production of PLGA nanoparticles through simple process control.
(Univ.-Prof. Mag. pharm. Dr. rer. nat. Eva Roblegg)

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